How to watch the Kansas City Chiefs-Buffalo Bills game: Time, TV, betting odds
AI-generated summary reviewed by our newsroom.
- Chiefs and Bills meet Nov. 2, 2025 at Highmark Stadium, 3:25 p.m. CT on CBS.
- Mahomes leads 5-4 vs. Allen in their tenth meeting; rivalry shapes AFC outcomes.
- Chiefs 5-3 favored by 1.5 vs. Bills 5-2; spread 1.5, over-under 52.5, bettors act.
Less than a hour after the Chiefs’ 28-7 victory over the Washington Commanders on “Monday Night Football,” thoughts turned to their next opponent:
The Buffalo Bills.
“We’ve got a big one coming up this week,” running back Kareem Hunt said. “We’re going to a tough environment.”
Chiefs vs. Bills, a battle of original AFL teams, has become one of the NFL’s top rivalries, with both teams regularly meeting in the postseason in this decade.
The Chiefs have won all four playoff matchups, including last year’s AFC Championship Game. But the Bills have owned the regular season, beating Kansas in four of five since 2020.
Sunday’s game will mark the 10th meeting between MVP quarterbacks Patrick Mahomes and Josh Allen, with Mahomes holding a 5-4 lead in such games.
Where and when is the Chiefs-Buffalo Bills game?
The Chiefs and Bills will meet at Highmark Stadium in Orchard Park, New York, on Sunday, Nov. 2, 2025. Kickoff time is 3:25 p.m. (Central Time).
What’s the channel (and radio info) for Chiefs-Bills?
The game will be televised by CBS. In Kansas City, it will be on KCTV (Channel 5). In Wichita, it’s on KWCH (Channel 12)
The game will also be broadcast on radio via KFNZ (96.5 FM) in the KC area, and KNSS (98.7 FM) in the Wichita area.
What’s the betting line for Chiefs-Bills?
The Chiefs (5-3) are a 1 1/2-point favorite over the Bills (5-2) and the over-under is 52 1/2. The Chiefs covered as an 11 1/2-point favorite in their 28-7 victory over the Commanders and are 5-2 against the spread.
This story was originally published October 28, 2025 at 5:15 AM with the headline "How to watch the Kansas City Chiefs-Buffalo Bills game: Time, TV, betting odds."