K-State Wildcats vs. OSU Cowboys: Big 12 football game prediction, odds, TV info
AI-generated summary reviewed by our newsroom.
- K-State enters Stillwater as an 18.5-point favorite despite injury losses.
- Oklahoma State ranks last in key Big 12 stats and has lost eight straight games.
- Market trimmed the spread from 20.5 as bettors reacted to K-State player absences.
Next up for Kansas State is a road game against the worst football team in the Big 12.
Oklahoma State has fallen on hard times. Coach Mike Gundy led the Cowboys to 18 straight bowl games, but his run of success came to an abrupt end and he was fired earlier this year.
Oklahoma State is now a bottom-feeder. It has lost eight straight games this season and 15 straight conference games over the past two years.
For that reason, K-State is favored by nearly three touchdowns on the road this week, even though the Wildcats remain two wins shy of bowl eligibility.
Can head coach Chris Klieman and the Wildcats take care of business? We will soon find out.
Here’s everything you need to know about the game ...
K-State at Oklahoma State: Game details
Kickoff: 11 a.m. Saturday
Where: Boone Pickens Stadium in Stillwater, Oklahoma
TV/stream: ESPNU
Radio: KCSP (610 AM) in Kansas City, KFH (1240 AM and 97.5 FM) in Wichita
The line: Kansas State by 18.5 with an O/U of 50.5.
Prediction
The betting line for this game topped out at 20.5 early in the week. But instead of pushing beyond three touchdowns, it has dropped a tad since then, presumably because starting linebacker Austin Romaine and No. 3 wide receiver Jerand Bradley are out for K-State with injuries.
It’s also possible that the market doesn’t have confidence in K-State as a big road favorite.
To be fair, that is not a role that has suited the Wildcats under Klieman. The Wildcats have gone 2-9-1 against the spread as road favorites since 2021, with five outright losses. The only time they covered a spread this high was in 2021 at Kansas.
Could K-State buck that trend and win by a big margin this weekend? Perhaps. Oklahoma State has lost eight straight games by an average of 29 points per contest. This is not a good Cowboys team.
Oklahoma State ranks last in the Big 12 in the most important statistical categories. It is allowing teams to score 38.8 points per game and to gain 443.8 yards per game. On offense, it is only averaging 297.7 yards and 15.2 points per game. Again, all four of those stats are worst in the conference ... by a wide margin.
The Wildcats should be able to move the ball efficiently against the Cowboys and win their first game at Boone Pickens Stadium since 2017.
But I’m not confident that K-State will cover the big spread.
K-State 34, Oklahoma State 17
Last game prediction: Texas Tech 24, K-State 20 ✅ (Final score: Texas Tech 43, K-State 20)
Season prediction record: 7-2
Season prediction record ATS: 7-2
Season record O/U: 5-4.
This story was originally published November 13, 2025 at 12:45 PM.