The Border War kicks off at 7 p.m.
The game will match the Jayhawks, 11-0, against the Tigers, 10-1, at Arrowhead Stadium and the winner will represent the North Division in the Big 12 championship game.
The teams, both winners Saturday, figure to advance in the polls after the weekend’s outcomes. With No. 2 Oregon losing on Thursday, Kansas, ranked fourth in the wire-service polls, and third in the Bowl Championship Series standing, could move to second in the BCS.
The top two teams in the final BCS standing play for the national championship.
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Missouri entered the weekend sixth in the polls and fifth in the BCS.
Saturday will mark the first time in the teams will face off as top 10 opponents.
Big 12 TV schedule for Nov. 23-24
11 a.m. (Central) Nebraska at Colorado (ABC)
2:30 p.m. Texas at Texas A&M (ABC)
2:30 p.m. Oklahoma State at Oklahoma (Fox Sports Net)
2:30 p.m. (Central) Kansas State at Fresno State (ESPN)
7 p.m. Kansas vs. Missouri at Arrowhead Stadium (ABC)